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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNB1
All Species:
16.06
Human Site:
T727
Identified Species:
50.48
UniProt:
Q14721
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14721
NP_004966.1
858
95878
T727
S
P
E
S
S
I
Y
T
T
A
S
A
K
T
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543042
858
96045
T727
S
P
E
S
S
I
Y
T
T
A
S
A
R
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q03717
857
95674
T726
S
P
E
S
S
I
Y
T
T
A
S
A
R
T
P
Rat
Rattus norvegicus
P15387
857
95619
T726
S
P
E
S
S
I
Y
T
T
A
S
A
R
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507252
997
108259
T664
P
G
Y
I
D
A
D
T
D
D
E
G
Q
G
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079257
876
99069
E744
R
T
P
S
K
S
P
E
K
H
M
A
I
D
F
Zebra Danio
Brachydanio rerio
XP_682848
827
92522
S697
S
S
I
L
S
D
H
S
I
L
S
P
E
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001195169
1105
121957
A924
T
I
T
S
A
E
D
A
G
S
N
G
S
H
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
97.4
N.A.
93.4
94
N.A.
53.7
N.A.
75.5
66.6
N.A.
N.A.
N.A.
N.A.
38.3
Protein Similarity:
100
N.A.
N.A.
98.5
N.A.
96.3
96.1
N.A.
60.5
N.A.
85
77.3
N.A.
N.A.
N.A.
N.A.
52.9
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
93.3
93.3
N.A.
6.6
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
13.3
N.A.
13.3
40
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
13
0
13
0
50
0
63
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
13
13
25
0
13
13
0
0
0
13
13
% D
% Glu:
0
0
50
0
0
13
0
13
0
0
13
0
13
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% F
% Gly:
0
13
0
0
0
0
0
0
13
0
0
25
0
13
0
% G
% His:
0
0
0
0
0
0
13
0
0
13
0
0
0
13
0
% H
% Ile:
0
13
13
13
0
50
0
0
13
0
0
0
13
0
0
% I
% Lys:
0
0
0
0
13
0
0
0
13
0
0
0
13
0
0
% K
% Leu:
0
0
0
13
0
0
0
0
0
13
0
0
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% N
% Pro:
13
50
13
0
0
0
13
0
0
0
0
13
0
0
50
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% Q
% Arg:
13
0
0
0
0
0
0
0
0
0
0
0
38
0
0
% R
% Ser:
63
13
0
75
63
13
0
13
0
13
63
0
13
0
13
% S
% Thr:
13
13
13
0
0
0
0
63
50
0
0
0
0
50
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
13
0
0
0
50
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _